Research Paper Volume 15, Issue 13 pp 6429—6444
Procoagulant genes may affect angiogenesis, epithelial-mesenchymal transition, survival prognosis and tumor immune microenvironment in patients with urothelial carcinoma
Figure 5. Effects of abnormal expression of coagulation-related genes on immune-related pathways. (A) GO analysis based on coagulation-related risk signature mainly enriched in the extracellular matrix pathways and MHC pathways. (B) KEGG analysis based on coagulation-related risk signature mainly enriched in the ECM receptor interaction pathways. (C) GSEA pathways were enriched for coagulation, EMT, hypoxia, WNTb-catenin, TGF-b pathways based on coagulation-related risk signature. (D) GSEA pathways were enriched for IL2-STAT, inflammatory response pathways based on coagulation-related risk signature. (E) GSEA pathways were enriched for IFNG pathways based on coagulation-related risk signature.