Research Paper Volume 15, Issue 12 pp 5569—5591

Expression, prognostic value and mechanism of SP100 family in pancreatic adenocarcinoma

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Figure 2. Relationship between expression levels of SP100 family members and clinicopathological features and prognosis of patients with PAAD. (A) The proportion of patients with N1 stage in PAAD patients with high SP100/SP110/SP140L expression was higher; (B) The proportion of patients with Stage IV stage in PAAD patients with high SP100/SP110 expression was higher; (C) The proportion of patients with smoking history and tumors located in the pancreatic head in PAAD patients with high SP140 expression was higher; (D) The increased expression level of SP100/SP110/SP140L were significantly correlated with shorter OS; (E) The increased expression level of SP100 were significantly correlated with shorter RFS; (F) SP100 family members showed high accuracy in predicting normal and neoplastic outcomes.